.Attributes Medicine, Posted online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic studies revealed that an unique reassortant popular descent of the Oropouche virus, which has been actually distributing in the western Amazon.com area of Brazil for regarding a years, is linked with the recent human outbreaks between 2022 as well as 2024.